Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III.

doi:10.1074/jbc.271.31.18947

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Article

Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III.

The Journal of biological chemistry - 2 Aug 1996

Mo J Y, Schaaper R M

Abstract excerpt

Escherichia coli DNA polymerase III holoenzyme is the replicative enzyme primarily responsible for the duplication of the E. coli chromosome. This process occurs with high accuracy, less than 10(-9) to 10(-10) errors being committed per base pair per round of replication. As a first step in under...

Topics

Bacterial Proteins
Base Sequence
DNA Polymerase III
DNA Replication
DNA, Bacterial
Escherichia coli
Escherichia coli Proteins
Lac Operon
Lac Repressors
Molecular Sequence Data
Mutation
Protein Conformation
Repressor Proteins
Substrate Specificity

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