Article
A Genome-Wide Assay Specifies Only GreA as a Transcription Fidelity Factor in Escherichia coli.
G3 (Bethesda, Md.) - 2 Jul 2018
Traverse Charles C, Ochman Howard
Abstract excerpt
Although mutations are the basis for adaptation and heritable genetic change, transient errors occur during transcription at rates that are orders of magnitude higher than the mutation rate. High rates of transcription errors can be detrimental by causing the production of erroneous proteins that need to be degraded. Two transcription fidelity factors, GreA and GreB, have previously been reported to stimulate the...
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