Article
The mutational specificity of two Escherichia coli dnaE antimutator alleles as determined from lacI mutation spectra.
Genetics - 1 Aug 1993
Schaaper R M
Abstract excerpt
In a companion study we have described the isolation of a series of mutants of Escherichia coli that replicate their DNA with increased fidelity. These mutants carry a mutation in the dnaE gene, encoding the alpha (polymerase) subunit of DNA polymerase III holoenzyme, which is responsible for the...
Topics
- Alleles
- Bacterial Proteins
- Bacteriophage T4
- Base Sequence
- DNA Polymerase III
- DNA, Bacterial
- DNA-Directed DNA Polymerase
- Escherichia coli
- Escherichia coli Proteins
- Frameshift Mutation
- Genes, Bacterial
- Kinetics
- Lac Operon
- Lac Repressors
- Molecular Sequence Data
- Mutation
- Repressor Proteins