Article
IgA2 genotyping by polymerase chain reaction (PCR) using allele-specific amplification primers.
Acta medica Okayama - 1 Feb 1996
Takata S, Yamamoto Y, Ishizu H
Abstract excerpt
A method of genotyping IgA2 alleles in the human immunoglobulin alpha 2 heavy chain constant region (C alpha 2 gene) was developed by using the polymerase chain reaction (PCR). By this method, the genotype was determined by discriminating base substitution in the 3'-flanking region of alleles, A2m*1 and A2m*2, which manifest A2m serum types, by nested PCR using allele-specific primers. Three types, IgA2*1/IgA2*1,...
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