Article
Haptoglobin genotyping by allele-specific polymerase chain reaction amplification.
Acta medica Okayama - 1 Aug 1998
Yano A, Yamamoto Y, Miyaishi S, Ishizu H
Abstract excerpt
We performed haptoglobin (Hp) genotyping by polymerase chain reaction using allele-specific primer-pairs. The major six genotypes of Hp were identified using this method. Among Japanese individuals living in Ehime and Okayama Prefectures, the allele frequencies were estimated to be Hp2 = 0.723 and Hp1s = 0.277. Genotyping of Hp was possible with 0.3 ng of DNA and with 0.125 microliter of blood. It was also...
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