Application of an allele-specific polymerase chain reaction to the direct determination of ABO blood group genotypes.

doi:10.1016/0888-7543(92)90292-z

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Article

Application of an allele-specific polymerase chain reaction to the direct determination of ABO blood group genotypes.

Genomics - 1 Apr 1992

Ugozzoli L, Wallace R B

Abstract excerpt

The allele-specific polymerase chain reaction (ASPCR) procedure has proven a powerful tool for the detection and analysis of known genetic polymorphisms. Here, we present a novel application of the ASPCR technique to determine the ABO genotypes of individuals without the need of family analysis....

Topics

ABO Blood-Group System
Alleles
Base Sequence
DNA
DNA Probes
Evaluation Studies as Topic
Female
Genotype
Humans
Male
Molecular Sequence Data
Pedigree
Polymerase Chain Reaction
Sensitivity and Specificity

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