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Article

Possible factors leading to a misjudgement of mutant frequencies in HPRT assay.

Mutation research - 5 Jul 1996

Khaidakov M, Glickman B W

Abstract excerpt

Interactions between cloning efficiency (CE) and mutant frequency (MF) in the HPRT clonal assay in in vitro study were analysed. In 12 separate reconstruction experiments with independent pairs of wild type (WT) and mutant (HPRT-) clones, the CE of WT cells (Group 1) and the recovery of mutant ce...

Topics

Humans
Hypoxanthine Phosphoribosyltransferase
Mutation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

PMID: 8692212
DOI: 10.1016/0027-5107(95)00253-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8692212-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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