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Article

p53 and MDM2 expression in oral squamous cell carcinoma.

Oncology - 1 Jan 2000

Matsumura T, Yoshihama Y, Kimura T, Shintani S, Alcalde R E

Abstract excerpt

The p53 tumor suppressor gene is the most commonly mutated gene in human cancer and is a frequent abnormality in oral squamous cell carcinoma and its precancerous lesions. MDM2 (murine double minute-2), a new proto-oncogene, may be associated with p53 gene products and may negatively affect the transcriptional activating function of p53. The purpose of this study was to investigate the incidence of MDM2 and its...

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Source

Identifiers

PMID: 8692535
DOI: 10.1159/000227578

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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