Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[The expression of Mdm2 protein and p53 mutation in lung squamous cell carcinomas and their clinicopathological significance].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases - 1 Mar 1999

Zhang J, Liu H, Li S, Gu C

Abstract excerpt

OBJECTIVE: In order to study the interrelation between p53 mutation, Mdm2 overexpression and pulmonary squamous cell carcinomas. METHODS: Forty-five pulmonary squamous cell carcinomas were investigated for expression of Mdm2 protein and p53 mutation using immunohistochemical techniques and PCR-SSCP. The findings were correlated with the clinicopathological features of carcinomas. RESULTS: (1) Mdm2 protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Squamous Cell
Share to Genes, p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphatic Metastasis

Share to Nuclear Proteins

Share to Polymorphism, Single-Stranded Conformational

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins c-mdm2

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 11812371

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[The expression of Mdm2 protein and p53 mutation in lung squamous cell carcinomas and their clinicopathological significance].PMID 11812371Read ↗

A molecular and immunohistochemical study of the MDM2 protein isoforms and p53 gene product in bronchogenic carcinoma.Semantic proximity Read ↗

[p53 alterations in human lung cancer and their correlation with clinicopathological features and prognosis].Semantic proximity Read ↗

MDM2 overexpression with alteration of the p53 protein and gene status in oral carcinogenesis.Semantic proximity Read ↗

p53 and MDM2 expression in oral squamous cell carcinoma.Semantic proximity Read ↗

MDM2 gene amplification and expression in non-small-cell lung cancer: immunohistochemical expression of its protein is a favourable prognostic marker in patients without p53 protein accumulationSemantic proximity Read ↗

mdm2 gene amplification and overexpression in non-small cell lung carcinomas with accumulation of the p53 protein in the absence of p53 gene mutations.Semantic proximity Read ↗

Wild-type p53 overexpression and its correlation with MDM2 and p14ARF alterations: an alternative pathway to non-small-cell lung cancer.Semantic proximity Read ↗

Association of p53 and mdm2 in the development and progression of non-small cell lung cancer.Semantic proximity Read ↗

Mdm2 overexpression and p14ARF inactivation are two mutually exclusive events in primary human lung tumorsSemantic proximity Read ↗

MDM2 mRNA expression is a favorable prognostic factor in non-small-cell lung cancerSemantic proximity Read ↗

P53 and MDM2 isoforms in blood from lung cancer patients.Semantic proximity Read ↗

Absence of mutations in the functional domains of the human MDM2 oncogene in non-small cell lung carcinomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.