Article
Alterations of the p14ARF-p53-MDM2 pathway in oral squamous cell carcinoma: MDM2 overexpression is a common event.
Oncology reports - 1 Oct 2005
Lim Kue Peng, Sharifah Hamid, Lau Shin Hin, Teo Soo-Hwang, Cheong Sok Ching
Abstract excerpt
The majority of global incidences of oral cancer occur in Asia, and the aetiology of oral cancer is different in Asia as it is in the West. However, whereas there is a growing understanding of the molecular mechanisms of oral cancer progression in the West, there is little progress in this understanding in Asia. In particular, the role of the p53 pathway in modulating cancer progression in Asian oral cancer...
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