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Article

P53 and MDM2 co-expression in tobacco and betel chewing-associated oral squamous cell carcinomas.

Journal of medical and dental sciences - 1 Dec 2001

Shwe M, Chiguchi G, Yamada S, Nakajima T, Maung K K, Takagi M, Amagasa T, Tsuchida N

Abstract excerpt

Oral cancers of tobacco and betel chewers represents a unique in-vivo model to understand the genotoxic effect of tobacco and betel carcinogens on oncogenes and tumor suppressor genes. Coordinated interactions of p53 and MDM2 play an important role in regulation of critical growth control gene following exposure to DNA damaging agents. The purpose of this study is to determine if the tumor suppressor function of...

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Source

Identifiers

PMID: 12160248

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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