Article
Polymorphism and smoking in bladder carcinogenesis.
British journal of urology - 1 May 1996
Chinegwundoh F I, Kaisary A V
Abstract excerpt
OBJECTIVE: To study the relationship between smoking, a cytochrome P-450 gene polymorphism and the development of bladder cancer. PATIENTS AND METHODS: The study comprised 126 patients with a diagnosis of bladder cancer from whom a full history was obtained. Genomic DNA was extracted from blood sampled from each patient and genotyping of the CYP2D6 locus, the gene responsible for debrisoquine hydroxylase...
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