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Article

Genetic Polymorphisms of CYP2A6 in a Case-Control Study on Bladder Cancer in Japanese Smokers.

Biological & pharmaceutical bulletin - 1 Jan 2016

Kumondai Masaki, Hosono Hiroki, Orikasa Kazuhiko, Arai Yoichi, Arai Tomio, Sugimura Haruhiko, Ozono Seiichiro, Sugiyama Takayuki, Takayama Tatsuya, Sasaki Takamitsu, Hirasawa Noriyasu, Hiratsuka Masahiro

Abstract excerpt

Several of the procarcinogens inhaled in tobacco smoke, the primary risk factor for bladder cancer, are activated by CYP2A6. The association between the whole-gene deletion of CYP2A6 (CYP2A6*4) and a reduced risk of bladder cancer was suggested in Chinese Han smokers. However, there is no evidence for association between the risk of bladder cancer and CYP2A6 genotypes in the Japanese population. Using genomic DNA...

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Identifiers

PMID: 26725431
DOI: 10.1248/bpb.b15-00604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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