Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metabolic cytochrome P450 genotypes and assessment of individual susceptibility to lung cancer.

Pharmacogenetics - 1 Dec 1992

Hirvonen A, Husgafvel-Pursiainen K, Anttila S, Karjalainen A, Sorsa M, Vainio H

Abstract excerpt

Three polymorphic cytochrome P450 genes that have attracted interest for their potential role in human pulmonary carcinogenesis, i.e. CYP1A1, CYP2D6 and CYP2E1, were studied in a population consisting of 106 lung cancer patients and 122 healthy controls. Polymorphism of the CYP2D6 gene encoding for debrisoquine hydroxylase was determined using XbaI restriction fragment length polymorphism (RFLP) analysis together...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytochrome P-450 CYP2D6
Share to Cytochrome P-450 Enzyme System

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Lung Neoplasms

Share to Mixed Function Oxygenases

Share to Oxidoreductases

Share to Polymorphism, Genetic

Share to Risk Factors

Source

Identifiers

PMID: 1306126
DOI: 10.1097/00008571-199212000-00003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metabolic cytochrome P450 genotypes and assessment of individual susceptibility to lung cancer.PMID 1306126Read ↗

Polymorphism in CYP1A1 and CYP2D6 genes: possible association with susceptibility to lung cancer.Semantic proximity Read ↗

PCR-based CYP2D6 genotyping for Finnish lung cancer patients.Semantic proximity Read ↗

Debrisoquin oxidation genotype and susceptibility to lung cancer.Semantic proximity Read ↗

Mutant genes of cytochrome P-450IID6, glutathione S-transferase class Mu, and arylamine N-acetyltransferase in lung cancer patients.Semantic proximity Read ↗

Human debrisoquine hydroxylase gene polymorphisms in cancer patients and controls.Semantic proximity Read ↗

New opportunities in cancer risk evaluation using PCR-based DNA analysis for CYP2D6.Semantic proximity Read ↗

Human CYP2D6 gene polymorphism in Slovene cancer patients and healthy controls.Semantic proximity Read ↗

The debrisoquine metabolic phenotype and DNA-based assays: implications of misclassification for the association of lung cancer and the debrisoquine metabolic phenotype.Semantic proximity Read ↗

Genetic polymorphism of CYP2D6 and lung cancer risk.Semantic proximity Read ↗

Relationship between the debrisoquine hydroxylase polymorphism and cancer susceptibility.Semantic proximity Read ↗

Identification of the primary gene defect at the cytochrome P450 CYP2D locus.Semantic proximity Read ↗

DNA haplotype dependency of debrisoquine 4-hydroxylase (CYP2D6) expression among extensive metabolisers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.