Article
CYP2D6 genotype and lung cancer risk according to histologic type and tobacco exposure.
Carcinogenesis - 1 Nov 1995
Stücker I, Cosme J, Laurent P, Cenée S, Beaune P, Bignon J, Depierre A, Milleron B, Hémon D
Abstract excerpt
Polymorphism for CYP2D6 was determined genetically as part of a hospital-based case-control study. The cases were males with a histologically confirmed lung cancer diagnosis, < 75 years old, and no previous cancer diagnosis. Male controls were matched for age, hospital and residence area. This study includes 301 cases and 310 controls. A DNA bank was established for 547 patients (89.5%), and genotypes for CYP2D6...
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