CYP2D6 genotype and lung cancer risk according to histologic type and tobacco exposure.

doi:10.1093/carcin/16.11.2759

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Article

CYP2D6 genotype and lung cancer risk according to histologic type and tobacco exposure.

Carcinogenesis - 1 Nov 1995

Stücker I, Cosme J, Laurent P, Cenée S, Beaune P, Bignon J, Depierre A, Milleron B, Hémon D

Abstract excerpt

Polymorphism for CYP2D6 was determined genetically as part of a hospital-based case-control study. The cases were males with a histologically confirmed lung cancer diagnosis, < 75 years old, and no previous cancer diagnosis. Male controls were matched for age, hospital and residence area. This st...

Topics

Adult
Aged
Cytochrome P-450 CYP2D6
Cytochrome P-450 Enzyme System
Genotype
Humans
Lung Neoplasms
Male
Middle Aged
Mixed Function Oxygenases
Polymorphism, Restriction Fragment Length
Risk
Smoking

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