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Article

Dose-dependent changes in the spectrum of mutations induced by ionizing radiation.

Radiation research - 1 Mar 2000

Schwartz J L, Jordan R, Sun J, Ma H, Hsieb A W

Abstract excerpt

We examined the influence of dose on the spectrum of mutations induced at the hypoxanthine guanine phosphoribosyltransferase (Hprt) locus in Chinese hamster ovary (CHO) cells. Independent CHO-K1 cell mutants at the Hprt locus were isolated from cells exposed to 0, 0.5, 1.5, 3.0 and 6.0 Gy (137)Cs gamma rays, and the genetic changes responsible for the mutations were determined by multiplex polymerase chain...

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Source

Identifiers

PMID: 10669553
DOI: 10.1667/0033-7587(2000)153[0312:ddcits]2.0.co;2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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