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Article

Induction of somatic mutations by low-dose X-rays: the challenge in recognizing radiation-induced events.

Journal of radiation research - 1 Apr 2018

Nagashima Haruki, Shiraishi Kumiko, Ohkawa Saori, Sakamoto Yuki, Komatsu Kenshi, Matsuura Shinya, Tachibana Akira, Tauchi Hiroshi

Abstract excerpt

It is difficult to distinguish radiation-induced events from spontaneous events during induction of stochastic effects, especially in the case of low-dose or low-dose-rate exposures. By using a hypersensitive system for detecting somatic mutations at the HPRT1 locus, we investigated the frequency and spectrum of mutations induced by low-dose X-rays. The mutant frequencies induced by doses of >0.15 Gy were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dose-Response Relationship, Radiation

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Source

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Identifiers

PMID: 29053826
DOI: 10.1093/jrr/rrx053
PMCID: PMC5941164

Genes

HPRT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Induction of somatic mutations by low-dose X-rays: the challenge in recognizing radiation-induced events.PMID 29053826Read ↗

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