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Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.

1 Apr 1996

Abstract excerpt

Hematopoietic stem cells (HSC) are multipotent cells that reside in the bone marrow and replenish all adult hematopoietic lineages throughout the lifetime of the animal. While experimenting with staining of murine bone marrow cells with the vital dye, Hoechst 33342, we discovered that display of Hoechst fluorescence simultaneously at two emission wavelengths revealed a small and distinct subset of whole bone...

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PMID: 8666936
DOI: 10.1084/jem.183.4.1797

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