A side order of stem cells: the SP phenotype.

doi:10.1634/stemcells.2005-0116

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Article

A side order of stem cells: the SP phenotype.

Stem cells (Dayton, Ohio) - 1 Jan 2006

Challen Grant A, Little Melissa H

Abstract excerpt

A defining property of murine hematopoietic stem cells (HSCs) is low fluorescence after staining with Hoechst 33342 and Rhodamine 123. These dyes have proven to be remarkably powerful tools in the purification and characterization of HSCs when used alone or in combination with antibodies directed against stem cell epitopes. Hoechst low cells are described as side population (SP) cells by virtue of their typical...

Topics

Animals
Benzimidazoles
Biomarkers
Drug Resistance, Multiple
Fluorescent Dyes
Hematopoietic Stem Cells
Mice
Organ Specificity
Phenotype
Rhodamine 123
Stem Cell Transplantation
Stem Cells

Source

Open in PubMed

Identifiers

PMID: 16449630
DOI: 10.1634/stemcells.2005-0116

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