Article
Identification and in vivo analysis of murine hematopoietic stem cells.
Methods in enzymology - 1 Jan 2010
Avagyan Serine, Amrani Yacine M, Snoeck Hans-Willem
Abstract excerpt
Hematopoietic stem cells (HSCs) can self-renew and give rise to all the cells of the blood and the immune system. As they differentiate, HSCs progressively lose their self-renewal capacity and generate lineage-restricted multipotential progenitor cells that in turn give rise to mature cells. The development of rigorous quantitative in vivo assays for HSC activity combined with multicolor flow cytometry and...
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