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Article

Phenotypic and functional characterization of the hematopoietic stem cell.

Stem cells (Dayton, Ohio) - 1 Jan 1997

Sharkis S J, Collector M I, Barber J P, Vala M S, Jones R J

Abstract excerpt

The purpose of this report is to demonstrate the phenotypic and functional characteristics of a primitive hematopoietic stem cell (HSC). We present evidence that an isolated murine HSC can repopulate the hematopoietic tissues of lethally irradiated recipient animals long term. By limiting dilution, as few as ten isolated stem cells can reconstitute mice for their lifetime. The stem cell which we have isolated...

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Identifiers

PMID: 9368323
DOI: 10.1002/stem.5530150807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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