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Article

Hematopoietic stem cell characterization and isolation.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Rossi Lara, Challen Grant A, Sirin Olga, Lin Karen Kuan-Yin, Goodell Margaret A

Abstract excerpt

Hematopoietic stem cells (HSCs) are defined by the capabilities of multi-lineage differentiation and long-term self-renewal. Both these characteristics contribute to maintain the homeostasis of the system and allow the restoration of hematopoiesis after insults, such as infections or therapeutic ablation. Reconstitution after lethal irradiation strictly depends on a third, fundamental property of HSCs: the...

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Identifiers

PMID: 21618082
DOI: 10.1007/978-1-61779-145-1_3
PMCID: PMC3621966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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