Effect of the cytochrome P-450IIE1 genotype on ethanol elimination rate in alcoholics and control subjects.

doi:10.1111/j.1530-0277.1996.tb01720.x

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Article

Effect of the cytochrome P-450IIE1 genotype on ethanol elimination rate in alcoholics and control subjects.

Alcoholism, clinical and experimental research - 1 Feb 1996

Ueno Y, Adachi J, Imamichi H, Nishimura A, Tatsuno Y

Abstract excerpt

We studied an influence of genetic polymorphisms in the cytochrome P-450IIE1 (CYP2E1) gene on ethanol elimination rate in alcoholic patients and healthy subjects. The CYP2E1 genotype was determined by polymerase chain reaction-restriction fragment length polymorphism method for 124 alcoholics and...

Topics

Adult
Aged
Alcoholism
Alleles
Cytochrome P-450 CYP2E1
Cytochrome P-450 Enzyme System
Ethanol
Female
Gene Expression Regulation, Enzymologic
Gene Frequency
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver Function Tests

Male

Metabolic Clearance Rate

Middle Aged

Oxidoreductases, N-Demethylating

Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 8659680
DOI: 10.1111/j.1530-0277.1996.tb01720.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8659680-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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