Article
Effect of the cytochrome P-450IIE1 genotype on ethanol elimination rate in alcoholics and control subjects.
Alcoholism, clinical and experimental research - 1 Feb 1996
Ueno Y, Adachi J, Imamichi H, Nishimura A, Tatsuno Y
Abstract excerpt
We studied an influence of genetic polymorphisms in the cytochrome P-450IIE1 (CYP2E1) gene on ethanol elimination rate in alcoholic patients and healthy subjects. The CYP2E1 genotype was determined by polymerase chain reaction-restriction fragment length polymorphism method for 124 alcoholics and 54 healthy subjects. There was no significant difference in the gene frequency of CYP2E1 between alcoholics and...
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