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Article

Association between polymorphisms of ethanol-metabolizing enzymes and susceptibility to alcoholic cirrhosis in a Korean male population.

Journal of Korean medical science - 1 Dec 2001

Lee H C, Lee H S, Jung S H, Yi S Y, Jung H K, Yoon J H, Kim C Y

Abstract excerpt

Alcohol is oxidized to acetaldehyde by alcohol dehydrogenase (ADH) and cytochrome P-4502E1 (CYP2E1), and then to acetate by aldehyde dehydrogenase (ALDH). Polymorphisms of these ethanol-metabolizing enzymes may be associated with inter-individual difference in alcohol metabolism and susceptibility to alcoholic liver disease. We determined genotype and allele frequencies of ALDH2, CYP2E1, ADH2, and ADH3 in male...

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Share to Liver Cirrhosis, Alcoholic

Source

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Identifiers

PMID: 11748356
DOI: 10.3346/jkms.2001.16.6.745
PMCID: PMC3054808

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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