Article
Genetic polymorphism of CYP2E1 and digestive tract alcohol damage among Polish individuals.
Alcoholism, clinical and experimental research - 1 May 2006
Cichoz-Lach Halina, Partycka Jadwiga, Nesina Irina, Wojcierowski Jacek, Słomka Maria, Celiński Krzysztof
Abstract excerpt
BACKGROUND: Genetic polymorphism of enzymes involved in alcohol metabolism plays a relevant role in etiopathogenesis of alcohol disease. The aim of the present study was to find in the Polish population the CYP2E1 genotypes that are likely to be responsible for higher susceptibility to alcohol disease of the liver and chronic alcohol pancreatitis. METHODS: The CYP2E1 genotype and c1 and c2 alleles frequency were...
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