Article
CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese.
Alcoholism, clinical and experimental research - 1 Jun 1995
Iwahashi K, Matsuo Y, Suwaki H, Nakamura K, Ichikawa Y
Abstract excerpt
The genotypes of the CYP2E1 and ALDH2 loci of alcoholic (alcohol dependence) and nonalcoholic (healthy) Japanese were investigated to examine the relationship between the polymorphism of CYP2E1 (C1/C2) and ALDH2 (ALDH2*1/ALDH2*2), and the susceptibility to alcoholism. There was no significant difference in C2 gene frequency between alcoholics (0.19) and nonalcoholics (controls) (0.20), whereas there was a...
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