CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese.

doi:10.1111/j.1530-0277.1995.tb01549.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese.

Alcoholism, clinical and experimental research - 1 Jun 1995

Iwahashi K, Matsuo Y, Suwaki H, Nakamura K, Ichikawa Y

Abstract excerpt

The genotypes of the CYP2E1 and ALDH2 loci of alcoholic (alcohol dependence) and nonalcoholic (healthy) Japanese were investigated to examine the relationship between the polymorphism of CYP2E1 (C1/C2) and ALDH2 (ALDH2*1/ALDH2*2), and the susceptibility to alcoholism. There was no significant difference in C2 gene frequency between alcoholics (0.19) and nonalcoholics (controls) (0.20), whereas there was a...

Topics

Alcohol Drinking
Alcoholism
Aldehyde Dehydrogenase
Alleles
Cytochrome P-450 CYP2E1
Cytochrome P-450 Enzyme System
Flushing
Gene Frequency
Genetics, Population
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Isoenzymes

Japan

Mitochondria, Liver

Oxidoreductases, N-Demethylating

Point Mutation

Polymorphism, Genetic

Risk Factors

Source

Open in PubMed

Identifiers

PMID: 7573775
DOI: 10.1111/j.1530-0277.1995.tb01549.x

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7573775-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese.PMID 7573775Read ↗

Relationship between alcoholism and CYP2E1 C/D polymorphism.Semantic proximity Read ↗

[Relationship between alcoholism and genotypes of acetaldehyde-metabolizing enzymes].Semantic proximity Read ↗

Genotype of cytochrome P450 2E1 and alcohol-related blood pressure elevation in Japanese men.Semantic proximity Read ↗

Polymorphisms of ethanol metabolizing enzyme genes and alcoholism.Semantic proximity Read ↗

Association between polymorphisms of ethanol-metabolizing enzymes and susceptibility to alcoholic cirrhosis in a Korean male population.Semantic proximity Read ↗

The effects of the ALDH2*1/2, CYP2E1 C1/C2 and C/D genotypes on blood ethanol elimination.Semantic proximity Read ↗

Genotypes of alcohol-metabolizing enzymes and the risk for alcoholic chronic pancreatitis in Japanese alcoholics.Semantic proximity Read ↗

Effect of ALDH2 and CYP2E1 gene polymorphisms on drinking behavior and alcoholic liver disease in Japanese male workers.Semantic proximity Read ↗

Genetic polymorphisms of cytochrome P4502E1 related to the development of alcoholic liver disease.Semantic proximity Read ↗

Association of genetic polymorphisms of alcohol-metabolizing enzymes with excessive alcohol consumption in Japanese men.Semantic proximity Read ↗

Comparison of genetic polymorphisms of CYP2E1, ADH2, and ALDH2 genes involved in alcohol metabolism in Koreans and four other ethnic groups.Semantic proximity Read ↗

Alcoholism and Alcoholic Organ Damage and Genetic Polymorphisms of Alcohol Metabolizing Enzymes in Chinese PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.