[The ethanol elimination pharmacokinetics--the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism].

Article

[The ethanol elimination pharmacokinetics--the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism].

Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studies & drug dependence - 1 Apr 1995

Iwahashi K, Miyatake R, Nakamura K, Suwaki H, Kinoshita H, Ameno K, Ijiri I, Ishikawa Y, Yoneyama H, Mendori T

Abstract excerpt

The effect of CYP2E1 upon the blood ethanol level was investigated. Blood ethanol concentrations in 4 volunteers whose ADH 2, ADH 3 and ALDH 2 genotypes were identical, were determined after intravenous administrations of 0.20 g/kg of ethanol by gas chromatography. The predicting 95% confidence b...

Topics

Aldehyde Dehydrogenase
Cytochrome P-450 Enzyme System
Ethanol
Genotype
Humans

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