Article
[Blood ethanol levels and the CTP2E1 C2 allele].
Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studies & drug dependence - 1 Jun 1994
Iwahashi K, Miyatake R, Suwaki H, Kinoshita H, Ameno K, Ijiri I, Ishikawa Y, Matsuo Y
Abstract excerpt
The effect of CYP2E1 upon the blood ethanol level was investigated. Blood ethanol concentrations in 2 volunteers whose ADH2, ADH3 and ALDH2 genotypes were identical, were determined after intravenous administrations of 0.15 g/kg of ethanol by gas chromatography. beta 60 (0.28 mg/ml/hr) of the blo...
Topics
- Aldehyde Dehydrogenase
- Alleles
- Cytochrome P-450 Enzyme System
- Ethanol
- Flushing
- Genotype
- Humans
- Oxidoreductases, N-Demethylating
- Polymerase Chain Reaction
- Polymorphism, Genetic
