Article
Fine mapping of smallest common regions of deletion on chromosome 12 in liver epithelial and hepatocellular carcinoma cell lines from B6C3F(1) and C3B6F(1) mice.
International journal of cancer - 15 Apr 2000
Ishizaki K, Ogawa K
Abstract excerpt
Loss of chromosomes frequently accompanies the establishment of hepatic cell lines in mice. Previous cytogenetic and allelotype studies have revealed that loss of chromosomes 4 and 12 is particularly common. In the present study, fine-deletion mapping was performed for chromosome 12 using 44 liver epithelial (LE) and hepatocellular carcinoma (HCC) cell lines derived from a hybrid between C3H/HeJ (C3H) and...
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