Allelic loss analysis of gamma-ray-induced mouse thymic lymphomas: two candidate tumor suppressor gene loci on chromosomes 12 and 16.

doi:10.1038/sj.onc.1201810

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Article

Allelic loss analysis of gamma-ray-induced mouse thymic lymphomas: two candidate tumor suppressor gene loci on chromosomes 12 and 16.

Oncogene - 28 May 1998

Matsumoto Y, Kosugi S, Shinbo T, Chou D, Ohashi M, Wakabayashi Y, Sakai K, Okumoto M, Mori N, Aizawa S, Niwa O, Kominami R

Abstract excerpt

A total of 429 gamma-ray-induced thymic lymphomas were obtained from F1 and backcross mice between BALB/c and MSM strains, about a half of which carried a p53-deficient allele. A genome-wide allelic loss analysis has revealed two loci exhibiting frequent allelic losses but no allelic preference,...

Topics

Animals
Chromosome Mapping
Female
Gamma Rays
Genes, Tumor Suppressor
Genotype
Loss of Heterozygosity
Lymphoma
Male
Mice
Mice, Inbred BALB C
Thymus Neoplasms
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 9652741
DOI: 10.1038/sj.onc.1201810

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9652741-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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