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Article

Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development.

Proceedings of the National Academy of Sciences of the United States of America - 14 May 1996

Kramer R, Bucay N, Kane D J, Martin L E, Tarpley J E, Theill L E

Abstract excerpt

Neuregulins are ligands for the erbB family of receptor tyrosine kinases and mediate growth and differentiation of neural crest, muscle, breast cancer, and Schwann cells. Neuregulins contain an epidermal growth factor-like domain located C-terminally to either an Ig-like domain or a cysteine-rich domain specific to the sensory and motor neuron-derived isoform. Here it is shown that elimination of the Ig-like...

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Identifiers

PMID: 8643489
DOI: 10.1073/pnas.93.10.4833
PMCID: PMC39365

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Source receipt: pubmed, retrieved 7 Sept 2026.

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