Article
Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development.
Proceedings of the National Academy of Sciences of the United States of America - 14 May 1996
Kramer R, Bucay N, Kane D J, Martin L E, Tarpley J E, Theill L E
Abstract excerpt
Neuregulins are ligands for the erbB family of receptor tyrosine kinases and mediate growth and differentiation of neural crest, muscle, breast cancer, and Schwann cells. Neuregulins contain an epidermal growth factor-like domain located C-terminally to either an Ig-like domain or a cysteine-rich...
Topics
- Animals
- Base Sequence
- Cranial Nerves
- DNA Primers
- Female
- Fetal Heart
- Gene Targeting
- Glycoproteins
- Immunoglobulins
- Immunohistochemistry
- In Situ Hybridization
- Male
- Mice
- Mice, Inbred C57BL
- Molecular Sequence Data
- Mutation
- Neuregulins
- RNA, Messenger