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Article

Ndrg4 is required for normal myocyte proliferation during early cardiac development in zebrafish.

Developmental biology - 15 May 2008

Qu Xianghu, Jia Haibo, Garrity Deborah M, Tompkins Kevin, Batts Lorene, Appel Bruce, Zhong Tao P, Baldwin H Scott

Abstract excerpt

NDRG4 is a novel member of the NDRG family (N-myc downstream-regulated gene). The roles of NDRG4 in development have not previously been evaluated. We show that, during zebrafish embryonic development, ndrg4 is expressed exclusively in the embryonic heart, the central nervous system (CNS) and the sensory system. Ndrg4 knockdown in zebrafish embryos causes a marked reduction in proliferative myocytes and results...

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Source

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Identifiers

PMID: 18407257
DOI: 10.1016/j.ydbio.2008.02.044
PMCID: PMC2800102

Genes

NDRG4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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