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Article

Myocardial Mycn is essential for mouse ventricular wall morphogenesis.

Developmental biology - 1 Jan 2013

Harmelink Cristina, Peng Yin, DeBenedittis Paige, Chen Hanying, Shou Weinian, Jiao Kai

Abstract excerpt

MYCN is a highly conserved transcription factor with multifaceted roles in development and disease. Mutations in MYCN are associated with Feingold syndrome, a developmental disorder characterized in part by congenital heart defects. Mouse models have helped elucidate MYCN functions; however its cardiac-specific roles during development remain unclear. We employed a Cre/loxp strategy to uncover the specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23063798
DOI: 10.1016/j.ydbio.2012.10.005
PMCID: PMC3508168

Genes

MYCN
NRG1
BMP10
CCND1
CCND2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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