Article
Involvement of the neuregulins and their receptors in cardiac and neural development.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Apr 1996
Carraway K L
Abstract excerpt
The neuregulin gene encodes a series of polypeptide growth factors that can influence the growth state of target vertebrate cells in culture. Recently, three studies have explored the in vivo function of the neuregulin signaling system in mice by disrupting the genes encoding the neuregulin ligand(1) and two of its receptors, ErbB2(2) and ErbB4(3). Each of the genes is essential for development, and aberrations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
