Article
The central region of the yeast U4 snRNA is not important for hammerhead catalysis, but may act as a domain spacer.
Nucleic acids symposium series - 1 Jan 1995
Hu J, Field D, Wang A, Friesen J D
Abstract excerpt
Several distinct domains of U4 small nuclear (sn)RNA interact with other components of the spliceosome and are essential for pre-mRNA splicing. We have previously shown that single point mutations (Hu et al., 1995) in the central domain of the yeast U4 snRNA do not effect cell growth. In contrast...
Topics
- Base Sequence
- DNA Primers
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Phenotype
- RNA Splicing
- RNA, Catalytic
- RNA, Fungal
- RNA, Small Nuclear
- Saccharomyces cerevisiae
- Spliceosomes