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Article

Structure-function analysis and genetic interactions of the Luc7 subunit of the Saccharomyces cerevisiae U1 snRNP.

RNA (New York, N.Y.) - 1 Sept 2016

Agarwal Radhika, Schwer Beate, Shuman Stewart

Abstract excerpt

Luc7 is an essential 261-amino acid protein subunit of the Saccharomyces cerevisiae U1 snRNP. To establish structure-function relations for yeast Luc7, we conducted an in vivo mutational analysis entailing N- and C-terminal truncations and alanine scanning of phylogenetically conserved amino acids, including two putative zinc finger motifs, ZnF1 and ZnF2, and charged amino acids within the ZnF2 module. We...

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Identifiers

PMID: 27354704
DOI: 10.1261/rna.056911.116
PMCID: PMC4986886

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Source receipt: pubmed, retrieved 7 Sept 2026.

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