Article
Psi35 in the branch site recognition region of U2 small nuclear RNA is important for pre-mRNA splicing in Saccharomyces cerevisiae.
The Journal of biological chemistry - 25 Feb 2005
Yang Chunxing, McPheeters David S, Yu Yi-Tao
Abstract excerpt
Pseudouridine 35 (psi35) in the branch site recognition region of yeast U2 small nuclear RNA is absolutely conserved in all eukaryotes examined. Pus7p catalyzes pseudouridylation at position 35 in Saccharomyces cerevisiae U2. The pus7 deletion strain, although viable in rich medium, is growth-disadvantaged under certain conditions. To clarify the function of U2 psi35 in yeast, we used this pus7 deletion strain to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
