More than half of yeast U1 snRNA is dispensable for growth.

doi:10.1093/nar/19.23.6367

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Article

More than half of yeast U1 snRNA is dispensable for growth.

Nucleic acids research - 11 Dec 1991

Siliciano P G, Kivens W J, Guthrie C

Abstract excerpt

Yeast U1 snRNA (568 nucleotides) is 3.5-fold larger than its mammalian counterpart (164 nucleotides) and contains apparent sequence homology only at the 5' and 3' ends. We have used deletion analysis to determine whether the yeast-specific U1 sequences play essential roles in vivo. Yeast cells ca...

Topics

Base Sequence
Blotting, Northern
Genes, Fungal
Kinetics
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Phenotype
RNA Splicing
RNA, Fungal
RNA, Small Nuclear
Yeasts

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