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Article

Formation of the 3' end of sea urchin U1 small nuclear RNA occurs independently of the conserved 3' box and on transcripts initiated from a histone promoter.

Molecular and cellular biology - 1 Sept 1992

Wendelburg B J, Marzluff W F

Abstract excerpt

The formation of the 3' end of vertebrate small nuclear RNAs (snRNAs) requires that transcription initiate from an snRNA promoter. There is a loosely conserved required box 5 to 20 nucleotides (nt) 3' of the gene. The sea urchin snRNA genes contain promoter elements different from those of the vertebrate snRNAs. They also contain a characteristic 3' 15-nt sequence which is conserved among different sea urchin...

Topics

Animals
Base Sequence
Cloning, Molecular
DNA
Histones
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
RNA, Small Nuclear
Sea Urchins
Transcription, Genetic

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Identifiers

PMID: 1508209
DOI: 10.1128/mcb.12.9.4132-4141.1992
PMCID: PMC360313

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1508209-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Formation of the 3' end of sea urchin U1 small nuclear RNA occurs independently of the conserved 3' box and on transcripts initiated from a histone promoter.PMID 1508209Read ↗

Two promoter elements are necessary and sufficient for expression of the sea urchin U1 snRNA gene.Semantic proximity Read ↗

Common factors direct transcription through the proximal sequence elements (PSEs) of the embryonic sea urchin U1, U2, and U6 genes despite minimal similarity among the PSEs.Semantic proximity Read ↗

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Stem-loop binding protein facilitates 3'-end formation by stabilizing U7 snRNP binding to histone pre-mRNA.Semantic proximity Read ↗

Sequences more than 500 base pairs upstream of the human U3 small nuclear RNA gene stimulate the synthesis of U3 RNA in frog oocytes.Semantic proximity Read ↗

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