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Article

A novel method for gene analysis of colorectal carcinomas using a crypt isolation technique.

Laboratory investigation; a journal of technical methods and pathology - 1 May 1996

Habano W, Sugai T, Nakamura S, Yoshida T

Abstract excerpt

Genetic studies of tumor masses require relatively pure populations of tumor cells. Substantial contamination by stromal cells, however, usually prevents detailed analysis of tumor cells. To improve the accuracy of gene analysis of tumor cells, a crypt isolation technique was introduced to separa...

Topics

Alleles
Base Sequence
Colorectal Neoplasms
DNA, Neoplasm
Female
Gene Deletion
Genes, p53
Genes, ras
Heterozygote
Humans
Intestinal Mucosa
Male
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Polymerase Chain Reaction

Polymorphism, Single-Stranded Conformational

Source

Identifiers

PMID: 8642788

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8642788-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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