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Article

Molecular analysis of isolated tumor glands from endometrial endometrioid adenocarcinomas.

Pathology international - 1 May 2015

Suga Yasuko, Sugai Tamotsu, Uesugi Noriyuki, Kawasaki Tomonori, Fukagawa Tomoyuki, Yamamoto Eiichiro, Ishida Kazuyuki, Suzuki Hiromu, Sugiyama Toru

Abstract excerpt

We studied the extensive molecular alterations of endometrial endometrioid adenocarcinoma (EEA) using a crypt isolation method. We analyzed copy number variation (CNV) using a single nucleotide polymorphism (SNP) array, genetic mutations (KRAS, BRAF, p53, PIK3CA), DNA methylation and microsatellite instability (MSI) status. In addition, loss of PTEN protein expression was examined. Increased chromosome copy...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25824640
DOI: 10.1111/pin.12274

Genes

KRAS
PTEN
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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