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Article

Detection of mutant K-ras DNA in plasma or serum of patients with colorectal cancer.

British journal of cancer - 1 Jan 1997

Kopreski M S, Benko F A, Kwee C, Leitzel K E, Eskander E, Lipton A, Gocke C D

Abstract excerpt

Increased understanding of the molecular basis of colorectal cancer and recognition that extracellular DNA circulates in the plasma and serum of cancer patients enables new approaches to detection and monitoring. We used a polymerase chain reaction (PCR) assay to demonstrate mutant K-ras DNA in the plasma or serum of patients with colorectal cancer. Plasma or serum was fractionated from the blood of 31 patients...

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Identifiers

PMID: 9374374
DOI: 10.1038/bjc.1997.551
PMCID: PMC2228153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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