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Article

p53, bcl-2 and Retinoblastoma Proteins as Long-Term Prognostic Markers in Localized Carcinoma of the Prostate

1 Jul 1997

Abstract excerpt

PURPOSE: The accumulation of p53 and bcl-2 gene products as well as the loss of the retinoblastoma (Rb) gene product have been associated with prostate cancer progression. We assessed whether the levels of immunoreactivity for p53, Rb and bcl-2 are better long-term predictors of disease specific survival than conventional pathological parameters of the primary tumor, such as Gleason score, capsular penetration,...

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PMID: 9186339
DOI: 10.1097/00005392-199707000-00040

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Source receipt: pubmed, retrieved 7 Sept 2026.

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