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Article

p53 status and prognosis of locally advanced prostatic adenocarcinoma: a study based on RTOG 8610.

Journal of the National Cancer Institute - 15 Jan 1997

Grignon D J, Caplan R, Sarkar F H, Lawton C A, Hammond E H, Pilepich M V, Forman J D, Mesic J, Fu K K, Abrams R A, Pajak T F, Shipley W U, Cox J D

Abstract excerpt

BACKGROUND: The p53 tumor suppressor gene (also known as TP53) is one of the most frequently mutated genes in human cancer. Several studies have shown that p53 mutations are infrequent in prostate cancer and are associated with advanced disease. PURPOSE: We assessed the prognostic value of identifying abnormal p53 protein expression in the tumors of patients with locally advanced prostate cancer who were treated...

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PMID: 8998185
DOI: 10.1093/jnci/89.2.158

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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