Article
Loss of heterozygosity of chromosome 3p sequences is an infrequent event in endometrial cancer.
Gynecologic oncology - 1 Feb 1996
Arlt M F, Herzog T J, Mutch D G, Goodfellow P J
Abstract excerpt
The genetic events associated with endometrial cancer are at present poorly understood. Frequent loss of heterozygosity (LOH) in a particular chromosomal region is often indicative of the involvement of a tumor suppressor gene. Previous studies are in disagreement over the involvement of a tumor suppressor gene(s) on the short arm of chromosome 3 in endometrial tumorigenesis. A set of 75 endometrial carcinomas...
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