Article
Loss of heterozygosity on the short arm of chromosome 3 in mesothelioma cell lines and solid tumors.
Genes, chromosomes & cancer - 1 Sept 1994
Zeiger M A, Gnarra J R, Zbar B, Linehan W M, Pass H I
Abstract excerpt
Cytogenetic analysis of mesothelioma cell lines and solid tumors has documented non-random chromosomal abnormalities on the short arm of chromosome 3 from 3p14 to 3p25. We therefore examined nine mesothelioma cell lines, their corresponding tumors, and 15 additional mesothelioma tumors for loss o...
Topics
- Alleles
- Base Sequence
- Chromosomes, Human, Pair 3
- DNA Mutational Analysis
- DNA, Neoplasm
- Genes, Tumor Suppressor
- Genetic Markers
- Genotype
- Humans
- Life Tables
- Mesothelioma
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Sequence Deletion
- Tumor Cells, Cultured
- von Hippel-Lindau Disease