Article
Allelotype of uterine cancer by analysis of RFLP and microsatellite polymorphisms: frequent loss of heterozygosity on chromosome arms 3p, 9q, 10q, and 17p.
Genes, chromosomes & cancer - 1 Feb 1994
Jones M H, Koi S, Fujimoto I, Hasumi K, Kato K, Nakamura Y
Abstract excerpt
Cancers in which mutations have been identified in putative tumor suppressor genes, such as the TP53 gene, the retinoblastoma (RBI) gene, the adenomatous polyposis coli (APC) gene, and the Wilms tumor (WTI) gene, frequently show loss of the corresponding allele on the homologous chromosome. To identify locations of tumor suppressor genes involved in uterine cancer, we examined loss of heterozygosity (LOH) by...
Topics
- Adenocarcinoma
- Alleles
- Base Sequence
- Carcinoma, Squamous Cell
- Chromosome Aberrations
- Chromosomes, Human, Pair 10
- Chromosomes, Human, Pair 17
- Chromosomes, Human, Pair 3
- Chromosomes, Human, Pair 9
- DNA, Neoplasm