Deletion mapping on the short arm of chromosome 3 in squamous cell carcinoma and adenocarcinoma of the lung.

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Article

Deletion mapping on the short arm of chromosome 3 in squamous cell carcinoma and adenocarcinoma of the lung.

Cancer research - 15 Feb 1992

Yokoyama S, Yamakawa K, Tsuchiya E, Murata M, Sakiyama S, Nakamura Y

Abstract excerpt

We examined loss of heterozygosity in 49 adenocarcinomas and 18 squamous cell carcinomas of the lung with 19 RFLP markers on the short arm of chromosome 3. Although no interstitial deletions were observed in any squamous cell carcinomas, interstitial or partial deletions were detected in 23 adenocarcinomas. Identification of two common regions of deletion in adenocarcinomas, at 3p21.3 and 3p14.1-21.1, suggested...

Topics

Adenocarcinoma
Adult
Aged
Alleles
Blotting, Southern
Carcinoma, Squamous Cell
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 1
DNA, Neoplasm
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Markers

Heterozygote

Humans

Lung Neoplasms

Male

Middle Aged

Neoplasm Staging

Source

Open in PubMed

Identifiers

PMID: 1346586

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1346586-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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