Article
The isfA mutation inhibits mutator activity and processing of UmuD protein in Escherichia coli recA730 strains.
Molecular & general genetics : MGG - 10 Apr 1996
Bebenek A, Pietrzykowska I
Abstract excerpt
Further studies on the isfA mutation responsible for anti-SOS and antimutagenic activities in Escherichia coli are described. We have previously shown that the isfA mutation inhibits mutagenesis and other SOS-dependent phenomena, possibly by interfering with RecA coprotease activity. The isfA mutation has now been demonstrated also to suppress mutator activity in E. coli recA730 and recA730 lexA51(Def) strains...
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