Article
The isfA mutation inhibits mutator activity and processing of UmuD protein in Escherichia coli recA730 strains.
Molecular & general genetics : MGG - 10 Apr 1996
Bebenek A, Pietrzykowska I
Abstract excerpt
Further studies on the isfA mutation responsible for anti-SOS and antimutagenic activities in Escherichia coli are described. We have previously shown that the isfA mutation inhibits mutagenesis and other SOS-dependent phenomena, possibly by interfering with RecA coprotease activity. The isfA mut...
Topics
- Antimutagenic Agents
- Bacterial Proteins
- Blotting, Western
- DNA-Directed DNA Polymerase
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial
- Genes, Dominant
- Genotype
- Lac Operon
- Mutation
- Protein Processing, Post-Translational
- Rec A Recombinases
- SOS Response, Genetics
- Tryptophan
- Ultraviolet Rays
- beta-Galactosidase