Article
A new mutation in Escherichia coli K12, isfA, which is responsible for inhibition of SOS functions.
Molecular & general genetics : MGG - 22 Jul 1995
Bebenek A, Pietrzykowska I
Abstract excerpt
A new mutation in Escherichia coli K12, isfA, is described, which causes inhibition of SOS functions. The mutation, discovered in a delta polA+ mutant, is responsible for inhibition of several phenomena related to the SOS response in polA+ strains: UV- and methyl methanesulfonate-induced mutagenesis, resumption of DNA replication in UV-irradiated cells, cell filamentation, prophage induction and increase in UV...
Topics
- Bacteriophage lambda
- Chromosome Mapping
- Conjugation, Genetic
- Escherichia coli
- Gene Deletion
- Genes, Bacterial
- Mutation
- Poly A
- Rec A Recombinases
- Recombination, Genetic
- SOS Response, Genetics